{"id":161,"date":"2011-08-18T14:58:00","date_gmt":"2011-08-18T14:58:00","guid":{"rendered":"http:\/\/lucasgferreira.wordpress.com\/2011\/08\/18\/paper-of-bears-frogs-meat-mice-and-men-complexity-of-factors-affecting-skeletal-muscle-mass-and-fat"},"modified":"2011-08-18T14:58:00","modified_gmt":"2011-08-18T14:58:00","slug":"paper-of-bears-frogs-meat-mice-and-men-complexity-of-factors-affecting-skeletal-muscle-mass-and-fat","status":"publish","type":"post","link":"https:\/\/blog.ufes.br\/lucasgf\/?p=161","title":{"rendered":"Paper: Of bears, frogs, meat, mice and men: complexity of factors affecting skeletal muscle mass and fat"},"content":{"rendered":"<div style=\"font-family:Arial,Helvetica,sans-serif\">&nbsp;Mais um trabalho que apresenta e discute o controle molecular do crescimento e atrofia musculares.<\/div>\n<div class=\"cit\" style=\"font-family:Arial,Helvetica,sans-serif\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16998828#\" title=\"BioEssays : news and reviews in molecular, cellular and developmental biology.\"><br \/><\/a><\/div>\n<h1 style=\"font-family:Arial,Helvetica,sans-serif;text-align:center\"><span style=\"font-size:large\"><\/span><\/h1>\n<div class=\"auths\" style=\"font-family:Arial,Helvetica,sans-serif\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16998828#\" title=\"BioEssays : news and reviews in molecular, cellular and developmental biology.\">Bioessays.<\/a> 2006 Oct;28(10):994-1009.<\/div>\n<div class=\"auths\" style=\"font-family:Arial,Helvetica,sans-serif\"><\/div>\n<div class=\"auths\" style=\"font-family:Arial,Helvetica,sans-serif\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed?term=%22Shavlakadze%20T%22%5BAuthor%5D\">Shavlakadze T<\/a>, <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed?term=%22Grounds%20M%22%5BAuthor%5D\">Grounds M<\/a>.<\/div>\n<div class=\"aff\" style=\"font-family:Arial,Helvetica,sans-serif\">\n<h3 class=\"label\"><i><span style=\"font-size:x-small\">School of Anatomy and Human Biology, The University of Western Australia, 6009, Western Australia. sthea@anhb.uwa.edu.au<\/span><\/i><\/h3>\n<\/div>\n<h3 style=\"font-family:Arial,Helvetica,sans-serif\">Abstract<\/h3>\n<div style=\"font-family:Arial,Helvetica,sans-serif;text-align:justify\">Extreme  loss of skeletal muscle mass (atrophy) occurs in human muscles that are  not used. In striking contrast, skeletal muscles do not rapidly waste  away in hibernating mammals such as bears, or aestivating frogs,  subjected to many months of inactivity and starvation. What factors  regulate skeletal muscle mass and what mechanisms protect against muscle  atrophy in some species? Severe atrophy also occurs with ageing and  there is much clinical interest in reducing such loss of muscle mass and  strength (sarcopenia). In the meat industry, a key aim is optimizing  the control of skeletal muscle growth and meat quality. The impaired  response of muscle to insulin resulting in diabetes, that is a  consequence of the metabolic impact of increasing obesity and fat  deposition in humans, is also of increasing clinical concern. Intensive  research in these fields, combined with mouse models, is reviewed with  respect to the molecular control of muscle growth (myogenesis) and  atrophy\/hypertrophy and fat deposition (adipogenesis) in skeletal  muscle, with a focus on IGF-1\/insulin signaling.<\/div>\n<div style=\"font-family:Arial,Helvetica,sans-serif\"><\/div>\n<div style=\"font-family:Arial,Helvetica,sans-serif\"><\/div>\n<div style=\"text-align:center\"><span style=\"font-family:Arial,Helvetica,sans-serif\">[ <\/span><a href=\"http:\/\/www.4shared.com\/document\/nPrqalpL\/Of_bears_frogs_meat_mice_and_m.html\">Download<\/a><span style=\"font-family:Arial,Helvetica,sans-serif\"> ]<\/span><\/div>\n<div class=\"blogger-post-footer\"><img width='1' height='1' src='https:\/\/blogger.googleusercontent.com\/tracker\/6438633595724989321-8911482042885728065?l=lucasgf-ufes.blogspot.com' alt='' \/><\/div>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp;Mais um trabalho que apresenta e discute o controle molecular do crescimento e atrofia musculares. Bioessays. 2006 Oct;28(10):994-1009. Shavlakadze T, Grounds M. School of Anatomy and Human Biology, The University of Western Australia, 6009, Western Australia. sthea@anhb.uwa.edu.au Abstract Extreme loss &hellip; <a href=\"https:\/\/blog.ufes.br\/lucasgf\/?p=161\">Continue lendo <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":9,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"_uag_custom_page_level_css":"","footnotes":""},"categories":[21,27,34,36],"tags":[],"class_list":["post-161","post","type-post","status-publish","format-standard","hentry","category-fisiologia","category-musculo","category-paper","category-plasticidade-muscular"],"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false,"post-thumbnail":false},"uagb_author_info":{"display_name":"Lucas Guimar\u00e3es Ferreira","author_link":"https:\/\/blog.ufes.br\/lucasgf\/?author=9"},"uagb_comment_info":14,"uagb_excerpt":"&nbsp;Mais um trabalho que apresenta e discute o controle molecular do crescimento e atrofia musculares. Bioessays. 2006 Oct;28(10):994-1009. Shavlakadze T, Grounds M. School of Anatomy and Human Biology, The University of Western Australia, 6009, Western Australia. sthea@anhb.uwa.edu.au Abstract Extreme loss &hellip; Continue lendo &rarr;","_links":{"self":[{"href":"https:\/\/blog.ufes.br\/lucasgf\/index.php?rest_route=\/wp\/v2\/posts\/161","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blog.ufes.br\/lucasgf\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blog.ufes.br\/lucasgf\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blog.ufes.br\/lucasgf\/index.php?rest_route=\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.ufes.br\/lucasgf\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=161"}],"version-history":[{"count":0,"href":"https:\/\/blog.ufes.br\/lucasgf\/index.php?rest_route=\/wp\/v2\/posts\/161\/revisions"}],"wp:attachment":[{"href":"https:\/\/blog.ufes.br\/lucasgf\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=161"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blog.ufes.br\/lucasgf\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=161"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blog.ufes.br\/lucasgf\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=161"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}