{"id":272,"date":"2012-02-06T16:21:17","date_gmt":"2012-02-06T18:21:17","guid":{"rendered":"http:\/\/blog.ufes.br\/lucasgf\/?p=272"},"modified":"2012-02-06T16:21:58","modified_gmt":"2012-02-06T18:21:58","slug":"regulacao-molecular-da-miogenese","status":"publish","type":"post","link":"https:\/\/blog.ufes.br\/lucasgf\/?p=272","title":{"rendered":"Regula\u00e7\u00e3o Molecular da Miog\u00eanese"},"content":{"rendered":"
Cold Spring Harb Perspect Biol.<\/a>\u00a02012 Feb 1;4(2). pii: a008342. doi: 10.1101\/cshperspect.a008342.<\/div>\n

Building muscle: molecular regulation of myogenesis.<\/h1>\n

Bentzinger CF<\/a>,\u00a0Wang YX<\/a>,\u00a0Rudnicki MA<\/a>.<\/p>\n

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The Sprott Centre for Stem Cell Research, Regenerative Medicine Program, Ottawa Health Research Institute, Ottawa, Ontario K1H 8L6, Canada.<\/span><\/em><\/h5>\n<\/div>\n
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Abstract<\/h3>\n

The genesis of skeletal muscle during embryonic development and postnatal life serves as a paradigm for stem and progenitor cell maintenance, lineage specification, and terminal differentiation. An elaborate interplay of extrinsic and intrinsic regulatory mechanisms controls myogenesis at all stages of development. Many aspects of adult myogenesis resemble or reiterate embryonic morphogenetic episodes, and related signaling mechanisms control the genetic networks that determine cell fate during these processes. An integrative view of all aspects of myogenesis is imperative for a comprehensive understanding of muscle formation. This article provides a holistic overview of the different stages and modes of myogenesis with an emphasis on the underlying signals, molecular switches, and genetic networks.<\/p>\n<\/div>\n

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PMID:\u00a022300977\u00a0<\/span>[PubMed – in process]<\/span><\/dt>\n
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Download do artigo completo: [4Shared<\/a>]<\/dt>\n<\/dl>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Cold Spring Harb Perspect Biol.\u00a02012 Feb 1;4(2). pii: a008342. doi: 10.1101\/cshperspect.a008342. Building muscle: molecular regulation of myogenesis. Bentzinger CF,\u00a0Wang YX,\u00a0Rudnicki MA. The Sprott Centre for Stem Cell Research, Regenerative Medicine Program, Ottawa Health Research Institute, Ottawa, Ontario K1H 8L6, Canada. … Continue lendo →<\/span><\/a><\/p>\n","protected":false},"author":9,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"_uag_custom_page_level_css":"","footnotes":""},"categories":[27,34,36,39],"tags":[],"class_list":["post-272","post","type-post","status-publish","format-standard","hentry","category-musculo","category-paper","category-plasticidade-muscular","category-sinalizacao-celular"],"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false,"post-thumbnail":false},"uagb_author_info":{"display_name":"Lucas Guimar\u00e3es Ferreira","author_link":"https:\/\/blog.ufes.br\/lucasgf\/?author=9"},"uagb_comment_info":14,"uagb_excerpt":"Cold Spring Harb Perspect Biol.\u00a02012 Feb 1;4(2). pii: a008342. doi: 10.1101\/cshperspect.a008342. Building muscle: molecular regulation of myogenesis. Bentzinger CF,\u00a0Wang YX,\u00a0Rudnicki MA. The Sprott Centre for Stem Cell Research, Regenerative Medicine Program, Ottawa Health Research Institute, Ottawa, Ontario K1H 8L6, Canada. … Continue lendo →","_links":{"self":[{"href":"https:\/\/blog.ufes.br\/lucasgf\/index.php?rest_route=\/wp\/v2\/posts\/272","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blog.ufes.br\/lucasgf\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blog.ufes.br\/lucasgf\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blog.ufes.br\/lucasgf\/index.php?rest_route=\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.ufes.br\/lucasgf\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=272"}],"version-history":[{"count":3,"href":"https:\/\/blog.ufes.br\/lucasgf\/index.php?rest_route=\/wp\/v2\/posts\/272\/revisions"}],"predecessor-version":[{"id":275,"href":"https:\/\/blog.ufes.br\/lucasgf\/index.php?rest_route=\/wp\/v2\/posts\/272\/revisions\/275"}],"wp:attachment":[{"href":"https:\/\/blog.ufes.br\/lucasgf\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=272"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blog.ufes.br\/lucasgf\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=272"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blog.ufes.br\/lucasgf\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=272"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}