{"id":81,"date":"2010-08-20T17:36:00","date_gmt":"2010-08-20T17:36:00","guid":{"rendered":"http:\/\/lucasgferreira.wordpress.com\/2010\/08\/20\/hmb-supplementation-clinical-and-athletic-performance-related-effects-and-mechanisms-of-action"},"modified":"2010-08-20T17:36:00","modified_gmt":"2010-08-20T17:36:00","slug":"hmb-supplementation-clinical-and-athletic-performance-related-effects-and-mechanisms-of-action","status":"publish","type":"post","link":"https:\/\/blog.ufes.br\/lucasgf\/?p=81","title":{"rendered":"HMB supplementation: clinical and athletic performance-related effects and mechanisms of action"},"content":{"rendered":"

Amino Acids.<\/a> 2010 Jul 6. [Epub ahead of print]<\/span><\/h3>\n

<\/span><\/div>\n
Zanchi NE<\/span><\/a><\/span>,<\/span><\/span> <\/span><\/span>Gerlinger-Romero F<\/span><\/a><\/span>,<\/span><\/span> <\/span><\/span>Guimar\u00e3es-Ferreira L<\/span><\/a><\/span>,<\/span><\/span> <\/span><\/span>de Siqueira Filho MA<\/span><\/a><\/span>,<\/span><\/span> <\/span><\/span>Felitti V<\/span><\/a><\/span>,<\/span><\/span> <\/span><\/span>Lira FS<\/span><\/a><\/span>,<\/span><\/span> <\/span><\/span>Seelaender M<\/span><\/a><\/span>,<\/span><\/span> <\/span><\/span>Lancha AH Jr<\/span><\/a><\/span>.<\/span><\/span><\/span><\/span><\/div>\n


<\/span><\/h3>\n

Abstract<\/span><\/span><\/h3>\n
Amino acids such as leucine and its metabolite alpha-ketoisocaproate (KIC), are returning to be the focus of studies, mainly because of their anti-catabolic properties, through inhibition of muscle proteolysis and enhancement of protein synthesis. It is clear that these effects may counteract catabolic conditions, as well as enhance skeletal muscle mass and strength in athletes. Moreover, beta-hydroxy-beta-methylbutyrate (HMB) has been shown to produce an important effect in reducing muscle damage induced by mechanical stimuli of skeletal muscle. This review aims to describe the general scientific evidence of KIC and HMB supplementation clinical relevance, as well as their effects (e.g., increases in skeletal muscle mass and\/or strength), associated with resistance training or other sports. Moreover, the possible mechanisms of cell signaling regulation leading to increases and\/or sparing (during catabolic conditions) of skeletal muscle mass are discussed in detail based on the recent literature.<\/span><\/div>\n
<\/div>\n","protected":false},"excerpt":{"rendered":"

Amino Acids. 2010 Jul 6. [Epub ahead of print] Zanchi NE, Gerlinger-Romero F, Guimar\u00e3es-Ferreira L, de Siqueira Filho MA, Felitti V, Lira FS, Seelaender M, Lancha AH Jr. Abstract Amino acids such as leucine and its metabolite alpha-ketoisocaproate (KIC), are returning to be the focus of studies, mainly … Continue lendo →<\/span><\/a><\/p>\n","protected":false},"author":9,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"_uag_custom_page_level_css":"","footnotes":""},"categories":[31,34,40],"tags":[],"class_list":["post-81","post","type-post","status-publish","format-standard","hentry","category-nutricao","category-paper","category-suplementacao"],"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false,"post-thumbnail":false},"uagb_author_info":{"display_name":"Lucas Guimar\u00e3es Ferreira","author_link":"https:\/\/blog.ufes.br\/lucasgf\/?author=9"},"uagb_comment_info":11,"uagb_excerpt":"Amino Acids. 2010 Jul 6. [Epub ahead of print] Zanchi NE, Gerlinger-Romero F, Guimar\u00e3es-Ferreira L, de Siqueira Filho MA, Felitti V, Lira FS, Seelaender M, Lancha AH Jr. Abstract Amino acids such as leucine and its metabolite alpha-ketoisocaproate (KIC), are returning to be the focus of studies, mainly … Continue lendo →","_links":{"self":[{"href":"https:\/\/blog.ufes.br\/lucasgf\/index.php?rest_route=\/wp\/v2\/posts\/81","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blog.ufes.br\/lucasgf\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blog.ufes.br\/lucasgf\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blog.ufes.br\/lucasgf\/index.php?rest_route=\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.ufes.br\/lucasgf\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=81"}],"version-history":[{"count":0,"href":"https:\/\/blog.ufes.br\/lucasgf\/index.php?rest_route=\/wp\/v2\/posts\/81\/revisions"}],"wp:attachment":[{"href":"https:\/\/blog.ufes.br\/lucasgf\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=81"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blog.ufes.br\/lucasgf\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=81"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blog.ufes.br\/lucasgf\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=81"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}